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Page 1
Loss of the Nuclear Pool of Ubiquitin Ligase CHIP/STUB1 in Breast Cancer Unleashes the MZF1-Cathepsin Pro-oncogenic Program.
Luan H, Mohapatra B, Bielecki TA, Mushtaq I, Mirza S, Jennings TA, Clubb RJ, An W, Ahmed D, El-Ansari R, Storck MD, Mishra NK, Guda C, Sheinin YM, Meza JL, Raja S, Rakha EA, Band V, Band H. Luan H, et al. Among authors: clubb rj. Cancer Res. 2018 May 15;78(10):2524-2535. doi: 10.1158/0008-5472.CAN-16-2140. Epub 2018 Mar 6. Cancer Res. 2018. PMID: 29510992 Free PMC article.
Endosomal-sorting complexes required for transport (ESCRT) pathway-dependent endosomal traffic regulates the localization of active Src at focal adhesions.
Tu C, Ortega-Cava CF, Winograd P, Stanton MJ, Reddi AL, Dodge I, Arya R, Dimri M, Clubb RJ, Naramura M, Wagner KU, Band V, Band H. Tu C, et al. Among authors: clubb rj. Proc Natl Acad Sci U S A. 2010 Sep 14;107(37):16107-12. doi: 10.1073/pnas.1009471107. Epub 2010 Aug 30. Proc Natl Acad Sci U S A. 2010. PMID: 20805499 Free PMC article.
Negative regulation of EGFR-Vav2 signaling axis by Cbl ubiquitin ligase controls EGF receptor-mediated epithelial cell adherens junction dynamics and cell migration.
Duan L, Raja SM, Chen G, Virmani S, Williams SH, Clubb RJ, Mukhopadhyay C, Rainey MA, Ying G, Dimri M, Chen J, Reddi AL, Naramura M, Band V, Band H. Duan L, et al. Among authors: clubb rj. J Biol Chem. 2011 Jan 7;286(1):620-33. doi: 10.1074/jbc.M110.188086. Epub 2010 Oct 12. J Biol Chem. 2011. PMID: 20940296 Free PMC article.
A combination of Trastuzumab and 17-AAG induces enhanced ubiquitinylation and lysosomal pathway-dependent ErbB2 degradation and cytotoxicity in ErbB2-overexpressing breast cancer cells.
Raja SM, Clubb RJ, Bhattacharyya M, Dimri M, Cheng H, Pan W, Ortega-Cava C, Lakku-Reddi A, Naramura M, Band V, Band H. Raja SM, et al. Among authors: clubb rj. Cancer Biol Ther. 2008 Oct;7(10):1630-40. doi: 10.4161/cbt.7.10.6585. Epub 2008 Oct 9. Cancer Biol Ther. 2008. PMID: 18769124 Free PMC article.